Best for
- Use when the user wants to run protein expression and purification (cell-free, E.
Source profileQuality 73/100
K-Dense-AI/scientific-agent-skills/skills/ginkgo-cloud-lab/SKILL.md
ginkgo-cloud-lab
Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run protein expression and purification (cell-free, E. coli, or Pichia), HiBiT or A280 or LabChip quantification, IVT mRNA/circRNA synthesis, thermal shift / developability assays, Echo-MS enzyme or analyte methods, SPR target onboarding, fluorescent pixel art, or otherwise interact with Ginkgo Cloud
- Source repository stars
- 31,966
- Declared platforms
- 0
- Static risk flags
- 1
- Last source update
- 2026-07-28
- Source checked
- 2026-07-28
Decision brief
What it does—and where it fits
Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud. ginkgo.
Not for
- Tasks that require unconfirmed production actions or broad system permissions.
- Environments where the pinned source and install steps cannot be inspected.
Compatibility matrix
Platform support, with evidence labels
| Platform | Status | Evidence | What to check |
|---|---|---|---|
| Codex | Not declared | No explicit evidence | Portability before use |
| Claude Code | Not declared | No explicit evidence | Portability before use |
| Cursor | Not declared | No explicit evidence | Portability before use |
| Gemini CLI | Not declared | No explicit evidence | Portability before use |
Installation
Inspect first. Install second.
The source command is displayed only when detected. A safe inspection prompt is always available so your agent can explain every action before execution.
Source-detected install commandSource
npx skills add https://github.com/K-Dense-AI/scientific-agent-skills --skill "skills/ginkgo-cloud-lab"Safe inspection promptEditorial
Inspect the Agent Skill "ginkgo-cloud-lab" from https://github.com/K-Dense-AI/scientific-agent-skills/blob/e7ac42510774624f327003c95b6650e2883bc01d/skills/ginkgo-cloud-lab/SKILL.md at commit e7ac42510774624f327003c95b6650e2883bc01d. List every install step, command, network request, credential, file read/write, external action, and rollback step. Explain whether it fits my task. Do not install or execute anything until I approve.
Workflow
What the source asks the agent to do
- 01
General Ordering Workflow
1. Select a protocol at https://cloud.ginkgo.bio/protocols 2. Configure parameters (number of proteins/samples/molecules/targets, replicates, plates) 3. Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; ve…
Select a protocol at https://cloud.ginkgo.bio/protocolsConfigure parameters (number of proteins/samples/molecules/targets, replicates, plates)Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; vendor catalog numbers for onboarding) - 02
Available Protocols
Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target).
Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target). - 03
Expression & Purification - In vitro
Review the “Expression & Purification - In vitro” section in the pinned source before continuing.
Review and apply the “Expression & Purification - In vitro” source section. - 04
Expression & Purification - Cell-free (E. coli CFPS)
Review the “Expression & Purification - Cell-free (E. coli CFPS)” section in the pinned source before continuing.
Review and apply the “Expression & Purification - Cell-free (E. coli CFPS)” source section. - 05
Expression & Purification - E. coli
Review the “Expression & Purification - E. coli” section in the pinned source before continuing.
Review and apply the “Expression & Purification - E. coli” source section.
Permission review
Static risk signals and limitations
Reads files
The documentation asks the agent to read local files, directories, or repositories.
The catalog is organized into **Expression & Purification** (in vitro / cell-free / E. coli / Pichia), **Characterization & Assay**, **Method & Target Onboarding**, and **Specialty**. Pick a protocol below, then read its reference file for Evidence record
Why each signal appears
EvidenceSourceComputedTestedEditorial
| Signal | Value | Evidence type | Meaning |
|---|---|---|---|
| Quality score | 73/100 | Computed | Documentation, specificity, maintenance, and trust rules |
| Repository stars | 31,966 | Source | Repository attention, not individual Skill quality |
| Compatibility | 0 platforms | Source | Declared in the catalog source record |
| Usage guide | automated source guide | Editorial | Generated or reviewed according to the visible evidence level |
Pinned source
Provenance and original SKILL.md
- Repository
- K-Dense-AI/scientific-agent-skills
- Skill path
- skills/ginkgo-cloud-lab/SKILL.md
- Commit
- e7ac42510774624f327003c95b6650e2883bc01d
- License
- MIT
- Collected
- 2026-07-28
- Default branch
- main
View the original SKILL.md
Ginkgo Cloud Lab
Overview
Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.
The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.
The catalog is organized into Expression & Purification (in vitro / cell-free / E. coli / Pichia), Characterization & Assay, Method & Target Onboarding, and Specialty. Pick a protocol below, then read its reference file for inputs, outputs, the automated workflow, and ordering details.
Available Protocols
Expression & Purification - In vitro
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| IVT mRNA/circRNA Synthesis | qPCR (mRNA or circRNA, 384-well) | $99/sample | up to 12 business days | Certified |
Expression & Purification - Cell-free (E. coli CFPS)
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Validate sequence expression | Go/no-go titer + purity (up to 1800 bp) | $39/sample | up to 10 days | Certified |
| Optimize expression conditions | DoE across 24 conditions | $199/sample | up to 11 days | Certified |
| Express + quantify (HiBiT) | Luminescence, no purification | $39/sample | up to 11 days | Certified |
| Express + purify (A280) | Strep-tag, A280 yield | $149/sample | up to 11 days | Certified |
| Express + purify minibinder | Strep-tag, A280, LabChip | $149/sample | up to 11 days | Certified |
| Express + purify (A280 + LabChip) | Strep-tag, A280 + purity/size | $159/sample | up to 12 days | Certified |
Expression & Purification - E. coli
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Express + quantify (HiBiT) | Luminescence (up to 384 constructs) | $79/sample | up to 3 weeks | Certified |
| Express + purify (A280) | His-tag, A280 yield | $199/sample | up to 3 weeks | Certified |
| Express + purify minibinder | His-tag, A280 yield | $199/sample | up to 3 weeks | Certified |
| Express + purify (A280 + LabChip) | His-tag, A280 + purity/size | $209/sample | up to 3 weeks | Certified |
Expression & Purification - Pichia
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Express + quantify (LabChip) | Secreted protein, size/purity (up to 96) | $89/sample | up to 4 weeks | Certified (New) |
Characterization & Assay
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Express + thermal shift | SYPRO Orange Tm (Tonset, TM1-3) | $159/sample | up to 12 days | Certified |
| Detect enzymatic products (Echo-MS) | Substrate/product by Echo-MS | $44/sample | up to 13 days | Beta |
Method & Target Onboarding
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Onboard Echo-MS method | Calibration curve, LOD/LOQ | $799/molecule | up to 3 weeks | Certified |
| Onboard SPR target | Validated SPR capture method | $1,399/target | up to 4 weeks | Beta |
Specialty
| Protocol | Readout | Price | Turnaround | Status |
|---|---|---|---|---|
| Generate fluorescent pixel art | UV photo, 7-color E. coli palette | $25/plate | up to 7 days | Beta |
Coming soon: Protein Expression and Binding Affinity Characterization (express + purify, then screen binding affinity against a target).
Choosing a Protocol
- Quick expressibility screen? Cell-free HiBiT ($39) or Validate sequence expression ($39).
- Need purified protein + yield? A280 tiers (cell-free or E. coli); add LabChip for purity/size.
- Difficult / membrane / disulfide / cofactor targets? Cell-free Optimize (24-condition DoE).
- Secreted or eukaryotic targets? Pichia expression.
- Screening de novo binders/minibinders? Cell-free or E. coli minibinder tiers, then SPR onboarding for kinetics.
- Enzyme activity / biocatalysis? Echo-MS enzymatic detection (onboard the analyte method first).
- Stability / developability ranking? Thermal shift assay.
- RNA (mRNA/circRNA)? IVT synthesis + qPCR.
General Ordering Workflow
- Select a protocol at https://cloud.ginkgo.bio/protocols
- Configure parameters (number of proteins/samples/molecules/targets, replicates, plates)
- Download the protocol's input template and upload inputs (FASTA/CSV/XLSX for sequence protocols; Design Tool for pixel art; vendor catalog numbers for onboarding)
- Add any special requirements in the Additional Details field
- Provide an email, agree to the protocol terms, and add to cart / submit to receive a feasibility report and price quote
For protocols not listed above, use the EstiMate chat (https://cloud.ginkgo.bio/estimate) to describe a custom protocol in plain language and receive a compatibility assessment and pricing.
Authentication
Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.
Key Infrastructure
- RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
- Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
- 70+ integrated instruments: Agilent Bravo liquid handlers, Beckman/Labcyte Echo acoustic dispensers, BMG PHERAstar / Tecan Spark readers, Revvity LabChip, Bio-Rad CFX Opus, Nicoya Alto SPR, SciEx Echo-MS, Inheco/Cytomat incubators, and more
- Nebula: Ginkgo's autonomous lab facility in Boston, MA
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